Mięsak gładkokomórkowy – niezwykle rzadki nowotwór złośliwy części nosowej gardła

Summary Malignant nasopharygeal neoplasms are relatively rare. Anaplastic nasopharyngeal carcinoma is the most common and the most malignant one. In this paper, we present a case of 56-year old patient with high-grade leiomyosarcoma of nasopharynx. The final diagnosis was achieved by using immunohistochemical methods – SMA (+), Caldesmon (+/−), Desmin (+/−), bcl 2 (+/−), EMA (−), S-100 (−), CD 34 (−), MIB 1 – 70% cells. The patient was successfully treated with radical radiotherapy IMRT technique (total dose 7000 cGy in 7 weeks). Currently, the patient has no symptoms and signs of the disease (oncological follow-up; CT imaging, PET-CT). This case is the first nasopharyngeal leiomyosarcoma reported in Poland, and probably the second one in the world.