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Trends in Bone Marrow Sampling and Core Biopsy Specimen Adequacy in the United States and Canada
- Source :
- American Journal of Clinical Pathology. 150:393-405
- Publication Year :
- 2018
- Publisher :
- Oxford University Press (OUP), 2018.
-
Abstract
- Objectives To assess bone marrow (BM) sampling in academic medical centers. Methods Data from 6,374 BM samples obtained in 32 centers in 2001 and 2011, including core length (CL), were analyzed. Results BM included a biopsy (BMB; 93%) specimen, aspirate (BMA; 92%) specimen, or both (83%). The median (SD) CL was 12 (8.5) mm, and evaluable marrow was 9 (7.6) mm. Tissue contraction due to processing was 15%. BMB specimens were longer in adults younger than 60 years, men, and bilateral, staging, and baseline samples. Only 4% of BMB and 2% of BMB/BMA samples were deemed inadequate for diagnosis. BM for plasma cell dyscrasias, nonphysician operators, and ancillary studies usage increased, while bilateral sampling decreased over the decade. BM-related quality assurance programs are infrequent. Conclusions CL is shorter than recommended and varies with patient age and sex, clinical circumstances, and center experience. While pathologists render diagnoses on most cases irrespective of CL, BMB yield improvement is desirable.
- Subjects :
- medicine.medical_specialty
medicine.diagnostic_test
Cross-sectional study
business.industry
Retrospective cohort study
General Medicine
Bone marrow examination
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
Multicenter study
030220 oncology & carcinogenesis
Biopsy
Medicine
Bone marrow sampling
Radiology
Bone marrow
business
Core biopsy
030215 immunology
Subjects
Details
- ISSN :
- 19437722 and 00029173
- Volume :
- 150
- Database :
- OpenAIRE
- Journal :
- American Journal of Clinical Pathology
- Accession number :
- edsair.doi...........6c0c92f00e3090e3aad11cf37e23a82d