Optimization of Ultrasound-Assisted Extraction of Phenolic Compounds from Areca Husk

In this paper, a method incorporating ultrasound technology has been developed to extract the phenolic compounds from areca husk. The experiments were carried out according to a three-variable, five-level central composite rotatable design, and the parameters of ethanol, extraction temperature and extraction time under optimum ultrasound-mediated condition were optimized by response surface methodology. The optimum extraction conditions were as follows: ethanol concentration, 41%; extraction temperature, 53C; and extraction time, 38 min. The ethanol concentration was the most significant parameter. Under the above-mentioned conditions, the experimental total phenolic content extracted from areca husk was 15.37 mg gallic acid equivalents in each gram. PRACTICAL APPLICATIONS In this manuscript, a method incorporating ultrasound technology has been developed, which can help to extract the phenolic compounds from areca husk.