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An Efficient Synthesis of N-Trifluoroacetyl Adriamycin-14-Valerate (AD-32)

Authors :
Cheng Ma
Yun-Hua Chen
Yanguang Wang
Yaozu Chen
Jian-feng Shi
Source :
Synthetic Communications. 29:3581-3586
Publication Year :
1999
Publisher :
Informa UK Limited, 1999.

Abstract

An eficent, one-pot procedure is reported for the synthesis of N-trifluoroacetyl adriamycin-14-valerate (AD-32, 3) from daunorubicin (1) in 35% overall yield.

Details

ISSN :
15322432 and 00397911
Volume :
29
Database :
OpenAIRE
Journal :
Synthetic Communications
Accession number :
edsair.doi...........6bdc2e8316b87080c862d601b1253892
Full Text :
https://doi.org/10.1080/00397919908085992