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A systematic review of sinonasal oncocytomas and oncocytic carcinomas: Diagnosis, management, and technical considerations
- Source :
- International Forum of Allergy & Rhinology. 7:514-524
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Background Oncocytomas and oncocytic carcinomas are rare tumors of the sinonasal cavity with the propensity for local invasion. This report and systematic review details a case of a nasal oncocytoma involving the lacrimal sac and provides an update of the current literature. Methods A systematic literature review was performed using PubMed and Ovid databases. The data obtained from published articles with sinonasal oncocytoma/oncocytic carcinoma as the primary diagnosis included patient demographics, presentation, radiographic and histologic findings, management, and recurrence rates. Results Twenty cases were identified. The most common symptoms were epistaxis (n = 11) and nasal obstruction (n = 11). Involvement of the nasal cavity was most common (n = 17), followed by the paranasal sinuses (n = 13) and nasolacrimal apparatus (n = 4). Recurrence occurred in 55% of cases. Recurrence was associated with invasion or infiltration found on histology or the presence of both invasion/infiltration and mitotic figures/pleomorphism (p < 0.05), with no significant relationship between recurrence and age at diagnosis (p = 0.42), sex (p = 0.65), and location of tumor (p = 0.14). The authors present the case of a 73-year-old woman with a 5-month history of worsening epistaxis and biopsy-proven oncocytoma. Complete surgical resection of the tumor using combined endonasal endoscopic and anterior orbitotomy approach is described. Conclusion Oncocytomas and oncocytic carcinomas are rare tumors of the sinonasal cavity with a high rate of local recurrence and orbital involvement. Surgical resection is the treatment of choice and complete resection can be achieved with an endoscopic endonasal approach.
- Subjects :
- Nasal cavity
medicine.medical_specialty
business.industry
Radiography
Histology
medicine.disease
Lacrimal sac
Surgery
03 medical and health sciences
0302 clinical medicine
Paranasal sinuses
medicine.anatomical_structure
Otorhinolaryngology
Pleomorphism (cytology)
030220 oncology & carcinogenesis
Diagnosis management
Immunology and Allergy
Medicine
Oncocytoma
030223 otorhinolaryngology
business
Subjects
Details
- ISSN :
- 20426976
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- International Forum of Allergy & Rhinology
- Accession number :
- edsair.doi...........69822d2f6ee7c1cdf5603e6f1a8f27f0