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Neutralization epitope in the envelope glycoprotein of simian retrovirus‐1 (SRV‐1) and identification of the virus receptor
- Source :
- Journal of Medical Primatology. 20:218-221
- Publication Year :
- 1991
- Publisher :
- Wiley, 1991.
-
Abstract
- We previously demonstrated that the area encompassing residues 147-162 of the envelope protein of simian retrovirus serotype-1 (SRV-1) is the target for rhesus anti-SRV-1 neutralizing antibodies. A peptide representing amino acids 142-167 of envelope protein (gp70) is capable of inducing virus-neutralizing antibodies in mice. The virus receptor was immunoprecipitated from Raji cells using gp70 as the ligand. Antibodies to peptide 142-167 inhibit the immunoprecipitation, indicating that the receptor recognizes residues 142-167 of the viral envelope protein.
Details
- ISSN :
- 16000684 and 00472565
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Journal of Medical Primatology
- Accession number :
- edsair.doi...........68b85fd154c6a7246c547673abf0c77d