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Toll-Like Receptor 3 (TLR3) Is Engaged in the Intracellular Survival of the Protozoan Parasite Leishmania (Leishmania) amazonensis

Authors :
Carolina T. Rath
Áislan C. Vivarini
José Vitorino dos Santos
Jorge M. Medina
Alessandra M. Saliba
Jeremy C. Mottram
Ana Paula C. A. Lima
Teresa Cristina Calegari-Silva
Renata M. Pereira
Ulisses G. Lopes
Source :
Infection and Immunity. 90
Publication Year :
2022
Publisher :
American Society for Microbiology, 2022.

Abstract

The protozoan parasite Leishmania (L.) amazonensis infects and replicates inside host macrophages due to subversion of the innate host cell response. In the present study, we demonstrate that TLR3 is required for the intracellular growth of L. (L.) amazonensis .

Details

ISSN :
10985522 and 00199567
Volume :
90
Database :
OpenAIRE
Journal :
Infection and Immunity
Accession number :
edsair.doi...........6843de6bc51c11bd1ce5fb5f39600673