Back to Search Start Over

Oligoclonal bands predict multiple sclerosis in children with optic neuritis

Authors :
Evangelos Kontopantelis
Peter Hofstetter
Rudolf Korinthenberg
Regina Hofmann
Stephanie Karch
Martin Häussler
Sascha Meyer
Michael Karenfort
Barbara Kornek
M. Piepkorn
Jörg Klepper
Mareike Schimmel
Isabel Brecht
S. Lutz
Astrid Blaschek
Janina Gburek-Augustat
Andreas Jenke
for Grace-Ms
Martin Smitka
Robert Weissert
Nicole Heussinger
Andreas Merkenschlager
Regina Trollmann
Kevin Rostasy
Peter Weber
Thomas Lücke
Gesa Vollrath
Martin Häusler
Kirsten Wenner
Mathias Buttmann
Peter Herkenrath
Source :
Annals of Neurology. 77:1076-1082
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

We retrospectively evaluated predictors of conversion to multiple sclerosis (MS) in 357 children with isolated optic neuritis (ON) as a first demyelinating event who had a median follow-up of 4.0 years. Multiple Cox proportional-hazards regressions revealed abnormal cranial magnet resonance imaging (cMRI; HR 5.94; 95% CI: 3.39-10.39; p

Details

ISSN :
03645134
Volume :
77
Database :
OpenAIRE
Journal :
Annals of Neurology
Accession number :
edsair.doi...........680d633cc5722d6055155fb2764cd318
Full Text :
https://doi.org/10.1002/ana.24409