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Fast, quantitative nucleoside protection under solvent-free conditions
- Source :
- Green Chemistry. 10:627
- Publication Year :
- 2008
- Publisher :
- Royal Society of Chemistry (RSC), 2008.
-
Abstract
- Persilylation of nucleoside hydroxyls was effected in quantitative yields under solvent-free conditions using a ball mill. In addition, one-pot persilylation and acylation of cytidine was performed as an exemplar reaction demonstrating the utility of solvent-free approaches to nucleoside chemistry.
Details
- ISSN :
- 14639270 and 14639262
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- Green Chemistry
- Accession number :
- edsair.doi...........67f2e365b6930c7979430abb64db45f6
- Full Text :
- https://doi.org/10.1039/b801455h