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Effects of Coleus forskohlii on Fat Storage in Ovariectomized Rats
- Source :
- YAKUGAKU ZASSHI. 125:449-453
- Publication Year :
- 2005
- Publisher :
- Pharmaceutical Society of Japan, 2005.
-
Abstract
- The antiobesity effects of Coleus forskohlii were investigated in ovariectomized (ovx) rats. Eight-week-old female Wistar rats were assigned to four groups: a sham-operated group fed the control diet (MF, sham-m) ; an ovx-m group fed the control diet; a sham-operated group fed the control diet containing 50 g/kg of Coleus forskohlii extract (sham-c) ; and an ovx-c group fed the control diet containing 50 g/kg of Coleus forskohlii extract. The body weight, adipose tissues, and cell diameter were investigated in ovx rats after Coleus forskohlii extract treatment. Administration of Coleus forskohlii extracts reduced body weight, food intake, and fat accumulation in ovx rats. Our results suggest that Coleus forskohlii may be useful in the treatment of obesity.
- Subjects :
- Pharmacology
Food intake
food.ingredient
Traditional medicine
Pharmaceutical Science
Adipose tissue
Coleus
Biology
medicine.disease
Body weight
Obesity
law.invention
food
Biochemistry
Fat accumulation
law
Ovariectomized rat
medicine
Phytotherapy
hormones, hormone substitutes, and hormone antagonists
Subjects
Details
- ISSN :
- 13475231 and 00316903
- Volume :
- 125
- Database :
- OpenAIRE
- Journal :
- YAKUGAKU ZASSHI
- Accession number :
- edsair.doi...........67f0824295a8c1c2ad7a2618713a8b34