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Effect of the HA/β-TCP Ratio on the Biological Performance of Calcium Phosphate Ceramic Coatings Fabricated by a Room-Temperature Powder Spray in Vacuum
- Source :
- Journal of the American Ceramic Society. 92:793-799
- Publication Year :
- 2009
- Publisher :
- Wiley, 2009.
-
Abstract
- Four calcium phosphate ceramic coatings, the less soluble hydroxyapatite (HA) coating, the more soluble β-tricalcium phosphate (β-TCP) coating, and two biphasic calcium phosphate (BCP) coatings with HA/β-TCP ratios of 70/30 and 30/70 were fabricated by spraying each corresponding powder onto a titanium substrate at room temperature (RT) in a vacuum, in order to investigate the effect of the HA/β-TCP ratio on the dissolution behavior and the cellular responses of the coating. No secondary phases, except for HA and β-TCP, were observed for the coatings in the X-ray diffraction results. The coating compositions were almost the same as those of the starting powders because the coating was conducted at RT. Microscopic examination of the coatings revealed crack-free and dense microstructures. The BCP coatings exhibited dissolution rates intermediate between those of the pure HA and β-TCP coatings. The dissolution rate of the coatings was largely dependent on their HA/β-TCP ratio. The cell proliferation and differentiation results indicated that the cellular responses of the coatings were not proportional to their dissolution rates. The 3HA-7TCP (HA/β-TCP ratio of 30/70) coating exhibited an optimal dissolution rate for excellent biological performance.
- Subjects :
- Materials science
Metallurgy
chemistry.chemical_element
Substrate (chemistry)
Powder Spray
Calcium
engineering.material
Microstructure
Phosphate
chemistry.chemical_compound
chemistry
Coating
Chemical engineering
visual_art
Materials Chemistry
Ceramics and Composites
visual_art.visual_art_medium
engineering
Ceramic
Dissolution
Subjects
Details
- ISSN :
- 15512916 and 00027820
- Volume :
- 92
- Database :
- OpenAIRE
- Journal :
- Journal of the American Ceramic Society
- Accession number :
- edsair.doi...........675ca87675aa7b5ed68534663e9c9042