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[Untitled]
- Source :
- Bulletin of Experimental Biology and Medicine. 130:886-891
- Publication Year :
- 2000
- Publisher :
- Springer Science and Business Media LLC, 2000.
-
Abstract
- Chemotherapy is an important method of antitumor therapy. Nephrotoxicity characteristic of many cytostatics, including platinum compounds, is a serious complication limiting the drug dose [4,5,7–9]. Platinum derivatives, in particular, cisplatin, are drugs of choice in the treatment of the majority of solid tumors. However, cisplatin induces a dose-dependent toxic damage to the kidneys [5,7,8,10].
- Subjects :
- Drug
Cisplatin
Chemotherapy
business.industry
media_common.quotation_subject
medicine.medical_treatment
Platinum compounds
chemistry.chemical_element
General Medicine
Limiting
Pharmacology
Antitumor therapy
General Biochemistry, Genetics and Molecular Biology
Nephrotoxicity
chemistry
medicine
business
Platinum
media_common
medicine.drug
Subjects
Details
- ISSN :
- 00074888
- Volume :
- 130
- Database :
- OpenAIRE
- Journal :
- Bulletin of Experimental Biology and Medicine
- Accession number :
- edsair.doi...........66c021d95dbabe8a8d52cda5231bb33f