Back to Search Start Over

[Untitled]

Authors :
N. E. Kushlinskii
S. V. Shiryaev
S. V. Topchieva
V. A. Gorbunova
S. G. Averinova
N. V. Lyubimova
A. V. Kashkadaeva
Source :
Bulletin of Experimental Biology and Medicine. 130:886-891
Publication Year :
2000
Publisher :
Springer Science and Business Media LLC, 2000.

Abstract

Chemotherapy is an important method of antitumor therapy. Nephrotoxicity characteristic of many cytostatics, including platinum compounds, is a serious complication limiting the drug dose [4,5,7–9]. Platinum derivatives, in particular, cisplatin, are drugs of choice in the treatment of the majority of solid tumors. However, cisplatin induces a dose-dependent toxic damage to the kidneys [5,7,8,10].

Details

ISSN :
00074888
Volume :
130
Database :
OpenAIRE
Journal :
Bulletin of Experimental Biology and Medicine
Accession number :
edsair.doi...........66c021d95dbabe8a8d52cda5231bb33f