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Anti-Ro Antibodies and Reversible Atrioventricular Block

Authors :
Roger Villuendas
Melania Martínez-Morillo
Irene Santos-Pardo
Antoni Bayes-Genis
Source :
New England Journal of Medicine. 368:2335-2337
Publication Year :
2013
Publisher :
Massachusetts Medical Society, 2013.

Abstract

To the Editor: Transplacental transfer of anti-Ro antibodies is a well-known cause of conduction defects and permanent atrioventricular block in newborns.1 In adults, conduction disturbances related to these antibodies are rare.2 We report a case of a 26-year-old woman with no history of this condition who was admitted to the hospital through the emergency department after having several syncopal episodes. Electrocardiography (ECG) performed while the patient was at rest showed complete atrioventricular block and ventricular escape rhythm associated with left bundle-branch block (Figure 1A). Laboratory evaluation included a positive test for antinuclear antibodies (with the HEp-2 cell substrate) at a . . .

Details

ISSN :
15334406 and 00284793
Volume :
368
Database :
OpenAIRE
Journal :
New England Journal of Medicine
Accession number :
edsair.doi...........66abe680990a1691303b65793ba973a5