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Design, synthesis and biological activity of some novel benzimidazole derivatives against Coxsackie virus B3
- Source :
- Chinese Chemical Letters. 20:921-923
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- A series of novel benzimidazole derivatives was synthesized and their anti-Coxsackie virus B 3 (CVB 3 ) activity was evaluated in VERO cells. Compounds 9 and 10 exhibited better inhibitory activity than those of ribavirin (RBV) with IC 50 values of 5.30 and 1.06 μg/mL, respectively.
Details
- ISSN :
- 10018417
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- Chinese Chemical Letters
- Accession number :
- edsair.doi...........6547de927fc8031a424d6cd2382f167a
- Full Text :
- https://doi.org/10.1016/j.cclet.2009.03.035