Enantioselective trimethylsilylcyanation of some aldehydes catalysed by titanium alkoxide–chiral dialkyl tartrate complexes

Authors :: Tohru Matsuda
Masahiko Hayashi
Nobuki Oguni
Source :: J. Chem. Soc., Perkin Trans. 1. :3135-3140
Publication Year :: 1992
Publisher :: Royal Society of Chemistry (RSC), 1992.
Abstract: Highly enantioselective trimethylsilylcyanation of various aldehydes with trimethylsilyl cyanide has been achieved with a modified Sharpless catalyst, consisting of titanium tetraisopropoxide [Ti(OPri)4] and chiral diisopropyl tartrate (DIPT). Asymmetric amplification was also observed in the trimethylsilylcyanation of benzaldehyde with a catalyst composed of Ti(OPri)4 and partially resolved DIPT.

Subjects :: chemistry.chemical_classification
Benzaldehyde
chemistry.chemical_compound
chemistry
Alkoxide
Polymer chemistry
Enantioselective synthesis
Organic chemistry
Tartrate
Diisopropyl tartrate
Trimethylsilyl cyanide
Aldehyde
Catalysis

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