ChemInform Abstract: N-Alkylation of Amino Acid Esters Using Sodium Triacetoxyborohydride

Authors :: Joshi M. Ramanjulu
Madeleine M. Joullié
Source :: ChemInform. 27
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: N-Alkylation of amino acid esters by reductive amination using sodium cyanoborohydride may often be problematic. Sodium triacetoxyborohydride was found to be a convenient reagent for this transformation. This methodology was employed to alkylate various amino acid methyl esters.

Subjects :: chemistry.chemical_classification
chemistry.chemical_compound
Sodium triacetoxyborohydride
chemistry
Sodium cyanoborohydride
Reagent
Organic chemistry
General Medicine
Alkylation
Reductive amination
Amino acid

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