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A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization
- Source :
- Antioxidants & Redox Signaling. 28:141-163
- Publication Year :
- 2018
- Publisher :
- Mary Ann Liebert Inc, 2018.
-
Abstract
- Aims: Microglia-mediated neuroinflammation plays an important role in focal ischemic stroke, a disorder with no effective therapeutic agents. Since microglial polarization to the M2 phenot...
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Physiology
Clinical Biochemistry
Inflammation
Biochemistry
03 medical and health sciences
0302 clinical medicine
medicine
Molecular Biology
Stroke
Neuroinflammation
General Environmental Science
Microglia
Activator (genetics)
business.industry
AMPK
Cell Biology
M2 polarization
medicine.disease
Surgery
030104 developmental biology
medicine.anatomical_structure
Ischemic stroke
General Earth and Planetary Sciences
medicine.symptom
business
Neuroscience
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15577716 and 15230864
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Antioxidants & Redox Signaling
- Accession number :
- edsair.doi...........63309ac25f60851f3ffbdf00a9ab20d4
- Full Text :
- https://doi.org/10.1089/ars.2017.7003