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Nanostructured lipid carriers for enhanced in vitro and in vivo schistosomicidal activity of praziquantel: effect of charge
- Source :
- Drug Development and Industrial Pharmacy. 47:663-672
- Publication Year :
- 2021
- Publisher :
- Informa UK Limited, 2021.
-
Abstract
- WHO considers praziquantel (PZQ) as the drug of choice for treatment of Schistosoma mansoni infection but this requires high dose due to poor solubility and first pass metabolism. The aim of this w...
- Subjects :
- Drug
media_common.quotation_subject
Adult worm
Pharmaceutical Science
Schistosomiasis
02 engineering and technology
Pharmacology
030226 pharmacology & pharmacy
03 medical and health sciences
First pass effect
0302 clinical medicine
In vivo
parasitic diseases
Drug Discovery
medicine
media_common
biology
Chemistry
Organic Chemistry
021001 nanoscience & nanotechnology
biology.organism_classification
medicine.disease
In vitro
Praziquantel
Schistosoma mansoni
0210 nano-technology
medicine.drug
Subjects
Details
- ISSN :
- 15205762 and 03639045
- Volume :
- 47
- Database :
- OpenAIRE
- Journal :
- Drug Development and Industrial Pharmacy
- Accession number :
- edsair.doi...........62e2a4015285f604df5a36bc79bdabc9
- Full Text :
- https://doi.org/10.1080/03639045.2021.1908339