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Enzyme assisted enantioselective synthesis of the alkaloid (+)-aloperine
- Source :
- Tetrahedron: Asymmetry. 15:2921-2925
- Publication Year :
- 2004
- Publisher :
- Elsevier BV, 2004.
-
Abstract
- The enantioselective synthesis of the lupinine alkaloid (+)-aloperine is described. The synthetic scheme presents three steps that are mediated by enzymes: kinetic resolution, oxidation of a primary alcohol to an aldehyde and oxidation of a secondary alcohol to a ketone.
Details
- ISSN :
- 09574166
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- Tetrahedron: Asymmetry
- Accession number :
- edsair.doi...........62660db776d992f8b49a7b6cea94d970
- Full Text :
- https://doi.org/10.1016/j.tetasy.2004.06.056