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Recent advances in gold nanoparticles for biomedical applications: from hybrid structures to multi-functionality
- Source :
- Journal of Materials Chemistry B. 7:3480-3496
- Publication Year :
- 2019
- Publisher :
- Royal Society of Chemistry (RSC), 2019.
-
Abstract
- Gold nanoparticles (Au NPs) are arguably the most versatile nanomaterials reported to date. Recent advances in nanofabrication and chemical synthesis have expanded the scope of Au NPs from classical homogeneous nanospheres to a wide range of hybrid nanostructures with programmable size, shape and composition. Novel physiochemical properties can be achieved via design and engineering of the hybrid nanostructures. In this review we discuss the recent progress in the development of complex hybrid Au NPs and propose a classification framework based on three fundamental structural dimensions (length scale, complexity and symmetry) to aid categorising, comparing and designing various types of Au NPs. Their novel functions and potential for biomedical applications will also be discussed, featuring point-of-care diagnostics by advanced optical spectroscopy and assays, as well as minimally invasive surgeries and targeted drug delivery using multifunctional nano-robots.
- Subjects :
- Materials science
Nanostructure
Biomedical Engineering
Nanotechnology
Multi functionality
02 engineering and technology
General Chemistry
General Medicine
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
0104 chemical sciences
Nanomaterials
Targeted drug delivery
Homogeneous
Colloidal gold
General Materials Science
0210 nano-technology
Subjects
Details
- ISSN :
- 20507518 and 2050750X
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Journal of Materials Chemistry B
- Accession number :
- edsair.doi...........622bab3b6e89be8ba1198af2aeb1a8c5