Stereoselective Synthesis of vic-Halohydrins via l-tert-Leucine-Catalyzed syn-Selective Aldol Reaction

Authors :: Takuya Kanemitsu
Atsushi Umehara
Takashi Itoh
Kazuhiro Nagata
Source :: Synlett. 23:453-357
Publication Year :: 2012
Publisher :: Georg Thieme Verlag KG, 2012.
Abstract: A convenient protocol is developed for the highly regio- and stereoselective aldol reaction of chloroacetone with aldehydes.

Subjects :: chemistry.chemical_classification
chemistry.chemical_compound
Chloroacetone
Aldol reaction
chemistry
Stereochemistry
Organocatalysis
Organic Chemistry
Enantioselective synthesis
L-tert-leucine
Stereoselectivity
Amino acid
Catalysis

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