Scaling Wet Fine Grinding Processes of Organic Particles Using Stirred Media Mills

This study presents an approach to scale up wet fine grinding processes of organic particles using stirred media mills. The process transfer is based on the calculation of grinding-relevant energy, which is transferred to the product by a model theory derived from mill-related values, especially geometric aspects. Its application was demonstrated by experimental work with two organic products, which were ground with different sizes and geometries of mills reaching from 20 to 900 mL grinding chamber volume under variation of process parameters.