Effects of selenium on coronary artery disease, type 2 diabetes and their risk factors: a Mendelian randomization study

Authors :: H. Simon Lam
C. Mary Schooling
Abigail A. Rath
Source :: European Journal of Clinical Nutrition. 75:1668-1678
Publication Year :: 2021
Publisher :: Springer Science and Business Media LLC, 2021.
Abstract: BACKGROUND The impact of selenium on coronary artery disease (CAD) and type 2 diabetes (T2D) remains unclear with inconsistent results from observational studies and randomized controlled trials. We used Mendelian randomization to obtain unconfounded estimates of the effect of selenium on CAD, T2D, lipids and glycemic traits. METHODS We applied genetic variants strongly (P

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