Synthesis of 1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones. II. Substitution at the 3-position with 2-aminoethyl and 2-aminopropyl side chains

Methods for the synthesis of 3-[2-aminoethyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones and 3-[2-aminopropyl]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones are described. The scope and limitations of the various methods are discussed.