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Microbial/enzymatic synthesis of chiral intermediates for pharmaceuticals
- Source :
- Enzyme and Microbial Technology. 31:804-826
- Publication Year :
- 2002
- Publisher :
- Elsevier BV, 2002.
-
Abstract
- There has been an increasing awareness of the enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enatioselective manner. Chiral intermediates and fine chemicals are in high demand both from pharmaceutical and agrochemical industries for the preparation bulk drug substances and agricultural products. In this review article, microbial/enzymatic processes have been described for the synthesis of chiral intermediates for anticancer drugs, antiviral agents, β3-receptor agonists, antihypertensive drugs, melatonin receptor agonists, anticholesterol drugs, and anti-Alzheimer’s drugs.
- Subjects :
- chemistry.chemical_classification
Drug
business.industry
media_common.quotation_subject
Bioengineering
Enzymatic synthesis
Applied Microbiology and Biotechnology
Biochemistry
Bulk drug
Enzyme
chemistry
Biotransformation
Biocatalysis
Organic chemistry
business
Biotechnology
Pharmaceutical industry
media_common
Subjects
Details
- ISSN :
- 01410229
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Enzyme and Microbial Technology
- Accession number :
- edsair.doi...........6089efcfbab0dd1a641dabee90fe0bfc