Side-Effects of Psychotropic Therapy

It has long been hypothesized that schizophrenia may be related to a specific injury of genetic material. There is some evidence of chromosomal abnormalities (DeLisi et al. 1988). Another study examined the repair defects seen in schizophrenic patients when their lymphocytes were treated with 4-nitroquinoline or gamma-radiation (Zasukhina 1987). However, no significant DNA-repair defect was observed by Magin et al. (1991).