Back to Search Start Over

Evaluation of antibacterial potentialities of Terminalia arjuna wight & arn leaf gall: an ethnomedicinal plant

Evaluation of antibacterial potentialities of Terminalia arjuna wight & arn leaf gall: an ethnomedicinal plant

Authors :
Hemanth Kumar N K
Poornachandra Rao K
Shobha Jagannath
Publication Year :
2022
Publisher :
Zenodo, 2022.

Abstract

In the current exploration an attempt has been made to assess the antibacterial potentialities of Terminalia arjuna Wight and Arn leaf galls. It belongs to the family Combretaceae commonly known as ‘Arjuna’, an important ethno medicinal plant. The different solvent extract of T. arjuna leaf gall were subjected to antibacterial activity, total phenol and total carbohydrate content estimation. The antimicrobial susceptibility was screened by means of well diffusion, disc diffusion, MIC and MBC methods. The result showed that the methanol extract was active against both gram negative and gram positive bacteria, when compared to other solvent extracts. The methanol extract of leaf gall showed optimum activity against Pesudomonas aeruginosa (MTCC-7903), Enterobacter aerogenes (MTCC-7325), Enterococcus faecalis (MTCC – 6845) and Staphylococcus aureus (MTCC- 3160). The highest amount of phenolic content was observed in methanol extract (93.62 µg GAE/mg of extract) followed by acetone >water >chloroform. The highest value of carbohydrate were observed in water extract (80.90 µg/mg of extract) followed by >acetone > methanol > chloroform. To the best of our knowledge, this is the first report of exploiting the antimicrobial properties of leaf gall of Terminalia arjuna. Our results indicated that the Terminalia arjuna leaf gall possess potential antibacterial activity. Keywords: T. arjuna, Methanol extract, Antibacterial activity. REFERENCES Ahmad, I. and Aquil, F. 2007. In vitro efficacy of bioactive extracts of 15 medicinal plants against ES ß - lactamase producing multidrug resistant enteric bacteria. Microbio. Res.162: 264 -275 Akram, M., Shahid, M. and Khan, A.U. 2007. Etiology and antibiotic resistance pattern of community acquired urinary infections in J N M C Hospital Aigarh India. Ann. Clin. Microbiol. 6: 4-13. Al-Emran, A., Ahmed, F., Kabir, M.D.S., Rahaman, M.D.M. and Shahed, S.M. 2001. Investigation of antimicrobial activity of Ethanolic Leaf-Fruit Extract of Terminalia arjuna against Multi-Drug Resistance (MDR) Bacteria in Bangladesh. J. Appl. Environ. Biol. Sci. 1(5): 90-95. Barreira, J.C.M., Ferreira, I.C.F.R., Oliveira, M.B.P.P. and Pereira, J.A. 2008. Antioxidant activities of the extracts from chestnut flower, leaf, skins and fruit. Food chem. 107: 1106-1113. Bhalodia, N.R. and Shukla, V.J. 2011. Antibacterial and antifungal activities from leaf extract of Cassia fistulal: An ethnomedicinal plant.Journal of Advanced Pharmaceutical Technology & Research2(2):104-109. Chin-Yuan, H., Chan-YuPei, C. and Chang, J. 2007. Antioxidant activity of extract from Polygonumcuspidatum. Biol. Res.40:12-21. Choen, M.L. 1992. Epidemiology of drug resistance: implications for post antimicrobial era. Science. 257:1050-1055. Chopra, I., Hodgson, J., Metcalf, B. and Poste, G. 1997. The search for antibacterial agents effective against bacteria resistance to multiple antibiotics. Antimicrob. Agent Chemotherap. 41: 497-503. Dodia, S. 2004 In vitro antifungal efficacy of essential oils against keratinophillic fungi isolated from patients of Tinea capitis. Geobios 31(1):77–78 Dulger, G. and Aki, C. 2009 Antimicrobial Activity of the Leaves of Endemic Stachys pseudopinardii in Turkey. Trop. J. Pharma. Res. 8(4): 371-375 Dwivedi, S. 2007. Terminalia arjuna Wight & Arn- a usefull drug for cardiovascular disorders. J. ethnopharmo. 114(2):114-129. Evan, J.S., Pattison, E. and Morris, F. 1986. Antimicrobial agents from plant cell culture, in secondary metabolities in plant cell culture, Editted by Morris P, Scraggs, A., Stafford, A. And Fowler, M. Cambridge university, London. Pp 12. Gazzaneo Ir, De lucena P.R.F., Paulino de Albu, Q.U. 2005. In vitro antioxidant activities of ocimum species: ocimum basilicum and ocimum sanctum, J. Ethnobiol. Ethnomed. Pp1: 9. Hart, C. A. and Karriuri, S. 1998. Antimicrobial resistance in developing countries. B.M.J. 317: 421-452. Hedge, J.E., Hofreiter, B.T., Whistler, R.L. and Be Miller, J.N. 1962. Carbohydrate chemistry. 17th ed. New York: Academic Press; pp. 11-12. Iwu, M.W., Duncan, A.R. and Okunji. C.O. 1999. New antimicrobials of plant origin. In: Perspectives on New Crops and New Uses. J. Janick ASHS Press, Alexandria, VA: 457-462. Kathirvel, A. and Sujatha, V. 2012. In vitro assessment of antioxidant and antibacterial properties of Terminalia chebula Retz. Leaves. Asian Pacific J. Tropi.Biomed. 12: 788-795. Lazos, E.S., Lafka, T.I., Lazou, A.E. and Sinanoglou, V.J. 2011. Phenolic and antioxidant potential of olive oil mill wastes. Food Chem. : 125: 92–98. Lukmanul, H.F., Girija, A. and Boopathy, R. 2008. Antioxidant property of selected Ocimum species and their secondary metabolite content. J. Med. Plants Res. 2(9): 250-257 Mathekga, A.D.M., Meyer, J.J.M., Horn, M.M. and Drews, S.E. 2000. An acylated phlorogucinol with antimicrobial properties from Helichrysum caespititium. Phytochemistry. 53:93-96. Miller, 1998. Botanical influences on cardiovascular disease. Altern. Med. Rev. 3(6): 413-420. Morris, A.K. and Masterton, R.G. 2002. Antibiotic resistance surveillance: action for international studies. J. antimicrobial ther. 49: 7-10 Naqvi, S.H.R., Asif, M., Rehman, A.B. and Ahmad, M. 2010. Evaluation of antimicrobial properties of Terminalia chebula Retz. Pak. J. Pharm. 27(1): 29-35 Ramya, S., Kalaivani, T., Rajashekaran, C., Jepachanderamohan, P., Alaguchamy, N., Kalayansundaram, M. and Jayakumararaj, R. 2008. Antimicrobial activity of aqueous extact of Bark, Root, Leaves and Fruits of Terminalia arjuna Wight & Arn. Ethnobotanical Leaflets 12: 1192-1197. Saleh, A.I., AI-Dosari, M., Abdul, M.S., Alsheikn, M and Abdel-kader, M.S. 2009. Evaluation of Hepatoprotective effect of Fumaria parviflora and Momardica balsaminaform Saudi Folk Medicine against experimentally induced liver injury in rats. Research journal of medicinal plants, 3(1): 9-15. Salie, F. Eagles, P.F.K. and Leng, H.M.J. 1996. Preliminary antimicrobial screening of four south African asteraceae species. J. ethnopharmo. 76: 347-354. Tomoko, N., Takashi, A., Hiromu, T., Tetsuro, I., Hiroko, M., Munekazu, I., Totshiyuki, T., Tetsuro, I., Fujio, A., Iriya, I., Tsutomu, N. and Kazuhito, W. 2002. Antibactrial activity of extracts reprarated from tropical and subtropical plants on methicillin-resistant staphylococcus. J. Health Sci. 48: 273-276. Valgas, C., Machado de Souza, S., Smânia, E.F.A. and Smânia, A. 2007 Screening methods to determine antibacterial activity of natural products. Braz. J. Microbio. 38:369-380. Viswanathan, V., Phadatare, A.G. and Mukne, A. 2014. Antimycobacterial and Antibacterial Activity ofAllium sativumBulbs.Indian J. Pharma. Sci.76(3): 256–261. Wang, J., Galgici, A., Kodali, S.K.B., Jayasuriya, H., Dorso, K., Vicente, F., Gonzale, A., Cully, D., Bramhill, D. and Singh, S. (2003). Discovery of a small molecule that inhibits cell division by blocking Fts Z, a novel therapeutic target of antibiotics. The J. Biological Chem., 278: 44424-44428. Warrier, P.K., Nambiar, V.P.K. and Ramaktty, C. 1996. Indian medicinal plants: a compendium of 500 species, (Eds. Warrier P.K., Nambiar, V.P.K. and Ramaktty, C. Vol. 5, 1st Ed. Orient Longman Limitted, Madras, India. 253-257. Yang, C., Chang, H., Lin, H. and Chuang L. 2013. Evaluation of antioxidant and antimicrobial activities from 28 Chinese herbal medicines. J. Pharmacogn. Phytochem. 2(1):294-305

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi...........5fe936f4b1cfd6250006e52a3bcad680
Full Text :
https://doi.org/10.5281/zenodo.7248607