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A phase 1 study evaluating ABT-414 in combination with temozolomide (TMZ) for subjects with recurrent or unresectable glioblastoma (GBM)

Authors :
Andrew M. Scott
David A. Reardon
Peter Ansell
Erica Gomez
Lisa Roberts-Rapp
Hui K Gan
Hao Xiong
JuDee Fischer
Lisa Fichtel
Priya Kumthekar
William Ames
Wijith Munasinghe
Kyle D. Holen
Michelle Pedersen
Martin J. van den Bent
Matthew W. Dudley
Ryan Merrell
Andrew B. Lassman
Source :
Journal of Clinical Oncology. 32:2021-2021
Publication Year :
2014
Publisher :
American Society of Clinical Oncology (ASCO), 2014.

Abstract

2021 Background: Patients (pts) with recurrent GBM have few treatment options and a very poor prognosis. GBM tumors often exhibit aberrant epidermal growth factor receptor (EGFR) proliferative sign...

Details

ISSN :
15277755 and 0732183X
Volume :
32
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........5fe534b791077c83308e4b8c3b494217