African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation

Authors :: Mingyang Cheng
Makoye Mhozya Kanyema
Yu Sun
Wenhui Zhao
Yiyuan Lu
Junhong Wang
Xiaoxu Li
Chunwei Shi
Jianzhong Wang
Nan Wang
Wentao Yang
Yanlong Jiang
Haibin Huang
Guilian Yang
Yan Zeng
Chunfeng Wang
Xin Cao
Source :: Journal of Virology. 97
Publication Year :: 2023
Publisher :: American Society for Microbiology, 2023.
Abstract: African swine fever virus (ASFV) is a large double-stranded DNA virus that primarily infects porcine macrophages. The ASFV genome encodes a large number of immunosuppressive proteins.

Full Text Access

Tools