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Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
- Source :
- Infection and Drug Resistance. 13:2637-2640
- Publication Year :
- 2020
- Publisher :
- Informa UK Limited, 2020.
-
Abstract
- Methods Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway. Results In these nasopharyngeal test paper samples, 38 kinds of bacteria, 10 kinds of viruses except SARS-CoV-2, nine kinds of fungi and three kinds of atypical pathogens had been found. There was some difference in microbial composition in the upper airway between severe and non-severe cases. Summary These results are important for us to study the effect of SARS-CoV-2 on the local microbial composition of upper airway and prevent opportunistic infection in severe patients.
- Subjects :
- 0301 basic medicine
Pharmacology
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Opportunistic infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
030106 microbiology
Microbial composition
macromolecular substances
Biology
medicine.disease
medicine.disease_cause
biology.organism_classification
Microbiology
03 medical and health sciences
0302 clinical medicine
Infectious Diseases
medicine
Pharmacology (medical)
030212 general & internal medicine
Airway
Bacteria
Coronavirus
Subjects
Details
- ISSN :
- 11786973
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Infection and Drug Resistance
- Accession number :
- edsair.doi...........5f5b300a7ac7b2e85845d43756956a92