γ-Irradiation-induced cell cycle arrest and cell death in a human submandibular gland cell line: Effect of E2F1 expression

Authors :: C D Lillibridge
Indu S. Ambudkar
Brian O'Connell
Anne C. O'Connell
Bruce J. Baum
Changyu Zheng
Source :: Journal of Cellular Physiology. 177:264-273
Publication Year :: 1998
Publisher :: Wiley, 1998.
Abstract: This study examined the effect of gamma-irradiation (5 and 10 Gy) on the human submandibular cell line (HSG). Radiation treatment (5 Gy and 10 Gy) induced a dose-dependent decrease in cell proliferation, with a G2/M arrest of the cell cycle, and an increase in cell death (cells with

Subjects :: Programmed cell death
Cell cycle checkpoint
Physiology
Cell growth
Clinical Biochemistry
Cell
Cell Biology
Cell cycle
Biology
Cell biology
medicine.anatomical_structure
Cell culture
medicine
E2F1
S phase

ISSN :: 10974652 and 00219541
Volume :: 177
Database :: OpenAIRE
Journal :: Journal of Cellular Physiology
Accession number :: edsair.doi...........5f2fc3930d0d481b82812ca5b1ba8d09
Full Text :: https://doi.org/10.1002/(sici)1097-4652(199811)177:2<264::aid-jcp8>3.0.co;2-l

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