Phase I study of IGF-methotrexate conjugate in the treatment of refractory malignancies expressing IGF-1R

Authors :: Yang Lu
Rozina A. Chowdhery
Hugh McTavish
Arkadiusz Z. Dudek
Sujata Gaitonde
Neeta K. Venepalli
Hui Xie
Robert J. Cabay
Frederick G. Behm
Rajyasree Emmadi
Source :: Journal of Clinical Oncology. 32:TPS2635-TPS2635
Publication Year :: 2014
Publisher :: American Society of Clinical Oncology (ASCO), 2014.
Abstract: TPS2635 Background: The insulin-like growth factor 1 receptor (IGF-1R) is overexpressed in multiple malignancies, including breast, prostate, lung, colorectal, CLL, T-ALL, and mantle cell lymphoma....

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