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Current and Future Nanotechnology Applications in the Management of Melanoma: A Review
- Source :
- Journal of Nanomedicine & Nanotechnology.
- Publication Year :
- 2015
- Publisher :
- OMICS Publishing Group, 2015.
-
Abstract
- Melanoma is a common malignancy with a high survival rate amongst those diagnosed early. The management of advanced disease is challenging, and current chemosurgery techniques have minimal effect on survival. Nanotechnology, offers great potential in revolutionizing the management of melanoma. New molecules and nanoparticles are designed worldwide in an aim to improve the diagnosis and spread to sentinel lymph nodes and other organs. Novel drug delivery systems are formulated to optimise the distribution and pharmacokinetics of chemotherapeutic agents while reducing their toxic effects. The scope of such molecules extends to therapeutic applications including photodynamic and photothermic therapy where light is converted to heat to combat neoplastic lesions; immunotherapy where nanoparticles are used as immunomodulators or vaccines against cancer cells; and gene therapy which targets pro-oncogenes on signal transduction pathways. This review paper presents current knowledge of the use of nanotechnology in the management of cancer, with a focus on melanoma.
- Subjects :
- business.industry
medicine.medical_treatment
Melanoma
Genetic enhancement
Biomedical Engineering
Pharmaceutical Science
Medicine (miscellaneous)
Cancer
Bioengineering
Photodynamic therapy
Immunotherapy
Bioinformatics
medicine.disease
Biotechnology
Applications of nanotechnology
Drug delivery
medicine
business
Survival rate
Subjects
Details
- ISSN :
- 21577439
- Database :
- OpenAIRE
- Journal :
- Journal of Nanomedicine & Nanotechnology
- Accession number :
- edsair.doi...........5e2f3a94be3b0097465fca6967c5d11c