Chemo-enzymatic synthesis of all four diastereoisomers of 1-fluoro-2-amino-indane

Authors :: Marius Réglier
Gilles Iacazio
Source :: Tetrahedron: Asymmetry. 16:3633-3639
Publication Year :: 2005
Publisher :: Elsevier BV, 2005.
Abstract: The four diastereoisomers of 1-fluoro-2-amino-indane have been synthesized in high enantiomeric excess with lipase resolution of cis-2-azido-1-indanol as a key step.

Subjects :: biology
Chemistry
Stereochemistry
Organic Chemistry
Diastereomer
Indane
Chemo enzymatic
Catalysis
Inorganic Chemistry
chemistry.chemical_compound
biology.protein
Organic chemistry
Physical and Theoretical Chemistry
Lipase
Enantiomeric excess

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