Antioxidant Properties of a New Water-Soluble Fullerene C70 Derivative

The search for effective antioxidants is an urgent medical and scientific problem, since oxidative stress causes a number of diseases and accelerates aging of human body. In this paper, we analyzed the ability of a new water-soluble fullerene C70 (F350) derivative to bind reactive oxygen species (ROS) when it was added to human embryonic lung fibroblasts (HELF). We found its non-toxic concentrations for cells, since the fullerene derivatives biosafety assessment is important for the potential application of the nanocomposites in medicine and biology. We also investigated the ability of this fullerene derivative to pass the cell membrane.