EXPERIMENTAL RESEARCH OF THE POSSIBILITIES OF INFLUENCE ON HEALING SMALL INTESTINAL ANASTOMOSIS

A promising area of further research is the use of a combination of components of tissue growth factors in combination with low-intensity electromagnetic effects of light radiation. Objective. Investigation of various methods of influence on the healing of sutures of the small intestinal anastomosis in conditions of peritonitis. Materials and methods. The experiment was conducted on 20 white Wistar male rats weighing 180-250 g, the content, care and methods of experimental work with which corresponded to the observance of the International Principles of the European Convention on the Protection of Vertebrate Animals (Strasbourg, 1985) Results. The research work reflects the results of an experimental study, the purpose of which was to develop a method of sealing the small intestinal anastomosis under peritonitis. The experiment was performed on 20 white Wistar male rats weighing about 250 grams. The possibilities of using physical (light of a certain wavelength) and biological (tissue growth factors) methods in the prevention and treatment of acute inflammatory reactions and stimulation of reparative processes are shown. It is noted that a promising direction for further research on methods for the prevention of insolvency of small bowel anastomoses is the use of electromagnetic effects of low intensity of the light spectrum in combination with the application of tissue growth factors. Conclusion. A promising direction for further research is the use of a combination of sealing lines with the application of components of tissue growth factors in combination with a low-intensity electromagnetic effect of light radiation.