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Synthesis ofRubrivivax gelatinosusLipid A and Analogues for Investigation of the Structural Basis for Immunostimulating and Inhibitory Activities

Authors :
Yoshiyuki Fukase
Yukari Fujimoto
Yo Adachi
Koichi Fukase
Yasuo Suda
Shoichi Kusumoto
Source :
Bulletin of the Chemical Society of Japan. 81:796-819
Publication Year :
2008
Publisher :
The Chemical Society of Japan, 2008.

Abstract

To elucidate the structural requirements for the endotoxic and antagonistic activities of lipid A derivatives, we have focused on the effects of the acyl moieties and acidic groups at the 1- and 4′...

Details

ISSN :
13480634 and 00092673
Volume :
81
Database :
OpenAIRE
Journal :
Bulletin of the Chemical Society of Japan
Accession number :
edsair.doi...........5c9b2620ec978869a1893e6a68f157fb