Simultaneous determination of sunitinib and its active metabolites N-desethylsunitinib (SU12662) in nude mice plasma by liquid chromatography tandem mass spectrometry and its application to a pharmacokinetic study

Authors :: Qinghong Su
Jian Li
Jingyun Li
Yin Yuan
Wei Lu
Siyuan Wang
Tianyan Zhou
Source :: Journal of Chinese Pharmaceutical Sciences. 24
Publication Year :: 2015
Publisher :: Journal of Chinese Pharmaceutical Sciences, 2015.

Subjects :: Chromatography
Pharmacokinetics
Liquid chromatography–mass spectrometry
Sunitinib
Chemistry
Lc ms ms
medicine
Pharmaceutical Science
Mice plasma
Active metabolite
medicine.drug

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