Abstract 5966: Melanoma revisited; The need for bio-banking and precision oncology, a study from a resource limited setting

Since the incidence of Malignant melanoma (MM) is rising, we propose high quality patient samples bio-bank for proper understanding of the disease and with time analyze on a large scale proteogenomics. There is increased need to support research and help improved patient care and outcome. Bio-banking in MM will provide high quality and well define tissue and bio-fluid specimens. Materials and Methods: Large scale sample collection were done for 22 patients with histological diagnosis of MM. The patients consent and hospital ethical approval was sorted for the study, with patients' fresh frozen tissue and blood samples collected, fractionated and stored in an automated bio-bank. Five patients however did not consent for bio-banking of their samples. Results: Patients that consented to sample collection had proteogenomic studies and other studies were done on their specimens with possibilities of new treatments for the patients and precision oncology for these patients tailored on their unique genomic landscape. Conclusion: Bio -banking on a large scale is possible and helpful in MM patient especially in our environment where most patients are lost to follow up and have high degree of resistance and mortality during chemo radiation treatment. Citation Format: Kasimu Umar Adoke, Sanusi Mohammed Haruna. Melanoma revisited; The need for bio-banking and precision oncology, a study from a resource limited setting [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5966.