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Hemoglobin Maputo : A New 6-Chain Variant (α2β2 47 (Cd6) Asp→Tyr) in Combination with Hemoglobin S, Identified by High Performance Liquid Chromatography (Hplc)

Authors :
L. Tentori
Henri Wajcman
Dominique Labie
J. P. Boissel
A. Massa
Marino Marinucci
Source :
Hemoglobin. 7:423-433
Publication Year :
1983
Publisher :
Informa UK Limited, 1983.

Abstract

During a routine hematological investigation, a slowly-moving hemoglobin variant was detected in a 2-year-old child from Maputo (Mozambique) in combination with hemoglobin S. Structural studies carried out by HPLC demonstrated a previously unreported amino acid substitution, β 47 (CD6) Asp→Tyr. The new hemoglobin variant has been named hemoglobin Maputo.

Details

ISSN :
1532432X and 03630269
Volume :
7
Database :
OpenAIRE
Journal :
Hemoglobin
Accession number :
edsair.doi...........5b07290cbfddf18698ae94194f560a6d