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Artificial-intelligence Assisted, Label-free Imaging of Sub-cellular Biology

Authors :
Fedor Getman
Arturo Burguete-Lopez
Maksim Makarenko
Andrea Fratalocchi
Source :
Biophotonics Congress 2021.
Publication Year :
2021
Publisher :
Optica Publishing Group, 2021.

Abstract

We discuss a technique enabling the recovery of refractive index and thickness maps of cells using bright-field microscopy and a suitably designed ultra-dark membrane. We show spatial resolutions as low as 50 nm, enabling organelle differentiation.

Details

Database :
OpenAIRE
Journal :
Biophotonics Congress 2021
Accession number :
edsair.doi...........5acedaceacbfe015b01c3ef085ad61fb
Full Text :
https://doi.org/10.1364/boda.2021.jtu4a.19