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Methyl Transfer from Methanol to Co-cobyrinate: A model for the Coenzyme B12 Dependent Methyltransferase?
- Source :
- Angewandte Chemie International Edition. 37:1283-1285
- Publication Year :
- 1998
- Publisher :
- Wiley, 1998.
-
Abstract
- With CoI corrins as supernucleophiles, methylation by methanol is achieved when the leaving group is activated by Zn2+ ions at elevated temperatures (see reaction below). This methylation reaction is the first model for the Co-dependent methyltransferase.
Details
- ISSN :
- 15213773 and 14337851
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Angewandte Chemie International Edition
- Accession number :
- edsair.doi...........5abf0f089379371c9a92534202c4f979
- Full Text :
- https://doi.org/10.1002/(sici)1521-3773(19980518)37:9<1283::aid-anie1283>3.0.co;2-n