SLN As Vehicle For A Model Drug: A Biophysical Study

Solid Lipid Nanoparticles (SLN) are well defined nanocarriers that reach the close proximity of the cell membrane and bring their content into the cell. We studied the distribution of the SLN within the cell cytoplasm trying to understand the internalization mechanism of these nanoparticles. Alveolar epithelial lung and mouse fibroblast cells were incubated with SLN. Our data suggest that SLN may be a compatible tool but still deserve further investigation.