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A Suzuki cross-coupling route to substituted aziridines

A Suzuki cross-coupling route to substituted aziridines

Authors :
Stephen C. Bergmeier
David J. Lapinsky
Source :
Tetrahedron Letters. 42:8583-8586
Publication Year :
2001
Publisher :
Elsevier BV, 2001.

Abstract

We have shown that the Suzuki cross-coupling reaction of olefinic aziridines is an effective route for the synthesis of substituted aziridines. This is the first example of a palladium coupling reaction applied to an aziridine-containing molecule. This method is complementary to other methods of aziridine synthesis utilizing organocuprate reagents.

Details

ISSN :
00404039
Volume :
42
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........5969c58cc68e09d8dfd998a2b890da09
Full Text :
https://doi.org/10.1016/s0040-4039(01)01903-7