ChemInform Abstract: Visible-Light-Activated Copper(I) Catalyzed Oxidative Csp-CspCross-Coupling Reaction: Efficient Synthesis of Unsymmetrical Conjugated Diynes Without Ligands and Base

A novel visible-light-promoted copper-catalysed process for the Csp–Csp cross-coupling reaction of terminal alkynes at room temperature is described. The current photochemical method is simple, highly functional group compatible, and more viable towards the construction of bio-active 1,3-unsymmetrical conjugated diynes without the need of bases/ligands, additives and expensive palladium/gold catalysts.