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Genetic susceptibility to obsessive-compulsive hoarding: the contribution of neurotrophic tyrosine kinase receptor type 3 gene1
- Source :
- Genes, Brain and Behavior. 7:778-785
- Publication Year :
- 2008
- Publisher :
- Wiley, 2008.
-
Abstract
- P 5 0.001] and rs7176429 (OR 5 2.78; P 5 0.0001), although only the latter remained significant after Bonferroni correction. Although the haplotype analysis did not show significant results, a more extended block of LD in the OCD hoarders with respect to the control group was observed, suggesting a lower haplotype diversity in these individuals. Our findings suggest that NTRK3 may contribute to the genetic susceptibility to hoarding in OCD and may constitute an interesting gene to focus on in studies of the genetic basis of obsessive–compulsive hoarding.
Details
- ISSN :
- 1601183X and 16011848
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Genes, Brain and Behavior
- Accession number :
- edsair.doi...........58eb51e5e8e959bb665e9b18b795de9d
- Full Text :
- https://doi.org/10.1111/j.1601-183x.2008.00418.x