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FACTORS WHICH CONTROL DNA PACKAGING MAY INFLUENCE THE CONTROL OF TRANSCRIPTION

Authors :
Jack D. Griffith
Publication Year :
1976
Publisher :
Elsevier, 1976.

Abstract

This paper describes recent work in this laboratory and others which indicates that DNA both in higher cells and in bacterial cells exists in a regularly condensed structure. Evidence from the study of purified DNA in the presence of mixtures of small molecules suggests that such mixtures confer a regular polyamine coating along the length of the DNA helix. The DNA-polyamine complex may be caused to condense by the hi stones in higher cells and by proteins as yet to be described in bacterial cells. Possibly these condensed structures are important in the regulation of cellular transcription.

Details

Database :
OpenAIRE
Accession number :
edsair.doi...........58de060cbb3b967c0de7dff79a900e70
Full Text :
https://doi.org/10.1016/b978-0-12-518550-9.50013-5