In-vivo demonstration of AO-OCT with a 3-sided pyramid wavefront sensor (Conference Presentation)

An adaptive optics optical coherence tomography (AO-OCT) system with a 3-sided pyramid wavefront sensor (P-WFS) is presented. Compared to the Shack-Hartmann WFS, the P-WFS promises better sensitivity in low-light scenarios and greater flexibility in pupil sampling. Key feature of the presented set-up is that part of the imaging light is used to illuminate the WFS. The double pass enables closed loop correction without beam modulation and speckle patterns in the sensor read-out are averaged out during scanning. The developed instrument is demonstrated with retinal images obtained in-vivo, where the cone mosaic is clearly visualized at ~4° eccentricity from the fovea.