ChemInform Abstract: Efficient Regioselective Synthesis of 3,4,5-Trisubstituted 1,2,4-Triazoles on the Basis of a Lithiation-Trapping Sequence

Authors :: Rosmara Mansueto
Filippo Maria Perna
Saverio Florio
Serena Perrone
Vito Capriati
Antonio Salomone
Source :: ChemInform. 46
Publication Year :: 2015
Publisher :: Wiley, 2015.
Abstract: An efficient regioselective mono-functionalization of 3,5-dimethyl-1,2,4-triazoles (I) is achieved by lithiation under optimized conditions and quenching with a variety of electrophiles.

Subjects :: Quenching (fluorescence)
Chemistry
Electrophile
Triazole derivatives
Regioselectivity
Sequence (biology)
General Medicine
Trapping
Combinatorial chemistry

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