Can The Charcoal Localization For Surgical Resection of Non-Palpable Breast Suspicious Lesions Be a Promising Method For Communities of Low Resources? Retrospective Observational Study

Background: Breast cancer is more frequently being detected as radiographic non-palpable lesions with the increased utilization of national screening programs. Moreover, the sizes of tumors detected have decreased in recent years, increasing the need for the accurate image-directed localization for surgical excision in a significant portion of cases. Although Wire guided localization has been the most commonly used method for many years, but inherent problems remain and limited its practice. Radio-guided occult lesion localization (ROLL) is currently the standard method of localization, however it is unavailable in most of low resources communities. This encourages us to use charcoal localization which is simple and cheap method of surgical localization of non-palpable suspicious breast lesions. Methods: This prospective study included 34 patients presented with non-palpable suspicious breast lesion (BIRADS 4 or 5). All patients were injected with 1-3 ml of sterilized 3% aqueous suspension of charcoal granules under guidance of ultrasound at the superficial border of the suspicious lesion and the track between the lesion and the needle entry point in the skin which occur at the future incision. This method was carried out in most patients one day before operation, however two patients underwent surgical excision after 6 days of localization without any interruption.Results: Thirty four patients had 36 Lesions. The median age was 43 years. The mean diameter of lesions 10.9 mm. Out of 36 lesions; the BIRADS as follow10 (4a), 12 (4b), 8 (4c), and 6 (5). Postoperative revealed 16 malignant lesions and 20 benign lesions. All 20 benign lesions were managed by wide local excision; All 14 BIRADS 4a lesions were proved to be benign. Sixteen malignant lesions were managed as the following; nine patients had breast conserving surgery, five patients had modified radical mastectomy (three patients had past history of modified radical mastectomy, one patient had Multicentric ILC and one patient had infiltrated safety margins on conservation), and one patient had Nipple Sparing Mastectomy with immediate breast reconstruction by Latissimus Dorsi Flap . There was no reaction nor infection reported in our study.Conclusion: Charcoal localization has many advantages and help surgical localization.